Weird Obesity Things

Weird obesity things:

  • Animals like feral rodents and lab animals are fatter now than a few decades ago
  • Something something gut bacteria
    • Identical twin mice were given intestinal microbes collected from either obese women or thin women. The mice were then fed the same diet in equal amounts. The mice with the fat lady bacteria became fatter than the other mice.
    • http://science.sciencemag.org/content/341/6150/1241214
  • Infectobesity
    • AD-36 is present in 30% of obese people and 11% of normal weight people. “Children with the virus averaged 52 pounds heavier than those with no signs of it and obese children with the virus averaged 35 pounds heavier than obese children with no trace of the virus. D-36 also causes obesity in chickens, mice, rats, and monkeys.”
    • https://en.wikipedia.org/wiki/Adenovirus_serotype_36
  • Most formerly obese people regain the weight they lost. Why?
    • “Reviews of the scientific literature on dieting (e.g., Garner & Wooley, 1991; Jeffery et al., 2000; Perri & Fuller, 1995) generally draw two conclusions about diets. First, diets do lead to short-term weight loss. One summary of diet studies from the 1970s to the mid-1990s found that these weight loss programs consistently resulted in participants losing an average of 5%–10% of their weight (Perri & Fuller, 1995). Second, these losses are not maintained. As noted in one review, “It is only the rate of weight regain, not the fact of weight regain, that appears open to debate” (Garner & Wooley, 1991, p. 740). The more time that elapses between the end of a diet and the follow-up, the more weight is regained.” 
    • http://escholarship.org/uc/item/2811g3r3#page-1 (pg.221-223 goes over the RCTs that are available)

This is not to say that I’m not on board with diet and exercise. I think poor eating and exercise habits explain a lot of the obesity we see. But it looks like there’s also some more complicated stuff going on, and a full explanation of obesity needs to address these things too (or explain why these studies are wrong).

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One Response to Weird Obesity Things

  1. Mike Powers says:

    There’s some indication that neurotransmitter production may be stimulated by obesity, and cause the body to defend obesity even when caloric restriction occurs.
    http://obesitycongress.conferenceseries.com/abstract/2014/defense-of-increased-body-weight-against-caloric-restriction-in-diet-induced-obesity-the-role-of-relaxin-3

    Like

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